Original articles in indexed journals - Integrative Biomedical Informatics

Queralt-Rosinach N, Piñero J, Bravo A, Sanz F, Furlong LI. DisGeNET-RDF: Harnessing the Innovative Power of the Semantic Web to Explore the Genetic Basis of Diseases. Bioinformatics, 2016; 32(14): 2236-8 . PMID: 27153650 . DOI: 10.1093/bioinformatics/btw214.

2016

Original articles in indexed journals - Structural Bioinformatics

Poglayen D, Marín-López MA, Bonet J, Fornes O, Garcia-Garcia J, Planas-Iglesias J, Segura J, Oliva B, Fernandez-Fuentes N. InteractoMIX: a suite of computational tools to exploit interactomes in biological and clinical research. Biochem Soc Trans, 2016; 44(3): 917-24 . PMID: 27284060 . DOI: 10.1042/BST20150001.

2016

Original articles in indexed journals - Integrative Biomedical Informatics

Digles D, Zdrazil B, Neefs JM, Van Vlijmen H, Herhaus C, Caracoti A. Brea J, Roibas B, Loza MI, Queralt-Rosinach N, Furlong LI, Gaulton A, Bartek L, Senger S, Chichester C, Engkvist O, Evelo CT, Franklin NI, Marren D, Ecker GF, Jacoby E. Open PHACTS computational protocols for in silico target validation of cellular phenotypic screens: knowing the knowns. MEDCHEMCOMM, 7 (6): 1237-1244 DOI: 10.1039/c6md00065g 2016.

2016

Original articles in indexed journals - Systems Pharmacology

Van Voorhis WC, Adams JH, Adelfio R, Ahyong V, Akabas MH, Alano P, Alday A, Alemán Resto Y, Alsibaee A, Alzualde A, Andrews KT, Avery SV et al (including Mestres J). Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond. PLoS Pathog, 2016; 12(7): e1005763. . PMID: 27467575 . DOI: 10.1371/journal.ppat.1005763. eCollection 2016.

2016

Original articles in indexed journals - Computational Science

Ferruz N, Tresadern G, Pineda-Lucena A, De Fabritiis G. Multibody cofactor and substrate molecular recognition in the myo-inositol monophosphatase enzyme. Sci Rep, 2016; 6: 30275 . PMID: 27440438 . DOI: 10.1038/srep30275.

2016

Original articles in indexed journals - Evolutionary Genomics

Faherty SL, Villanueva-Cañas JL, Klopfer PH, Alba MM, Yoder AD. Gene expression profiling in the hibernating primate, Cheirogaleus medius. Genome Biol Evol, 2016; 8 (8): 2413-2426 . PMID: 27412611 . DOI: 10.1093/gbe/evw163.

2016

Original articles in indexed journals - Functional Genomics

Kannan L, Ramos M, Re A, El-Hachem N, Safikhani Z, Gendoo DMA, Davis S, Gomez-Cabrero D, Castelo R, Hansen KD, Carey VJ, Morgan M, Culhane AC, Haibe-Kains B, Waldron L. Public data and open source tools for multi-assay genomic investigation of disease. Brief Bioinform, 2016; 17 (4): 603-615; SI . PMID: 26463000 . DOI: 10.1093/bib/bbv080 JUL 2016.

2016

Original articles in indexed journals - Structural Bioinformatics

Wright R, Lioutas A, Le Dily F, Soronellas D, Pohl A, Bonet J, Nacht AS, Samino S, Puchades Carrasco L, Font-Mateu J, Vicent GP, Wierer M, Trabado MA, Schelhorn C, Carolis C, Macias MJ, Yanes O, Oliva B, Beato M. ADP-ribose-derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling. Science, 2016; 352 (6290), 1221-1225 . PMID: 27257257 . DOI: 10.1126/ science. aad9335.

2016

Original articles in indexed journals - Integrative Biomedical Informatics

Bravo A, Li TS, Su AI, Good BM, Furlong LI. Combining machine learning, crowdsourcing and expert knowledge to detect chemical-induced diseases in text. Database (Oxford) 2016 . PMID: 27307137 . DOI: 10.1093/database/baw094.

2016

Original articles in indexed journals - Structural Bioinformatics

Alvarez-Cienfuegos A, Nuñez-Prado N, Compte M, Cuesta AM, Blanco-Toribio A, Harwood SL, Villate M, Merino N, Bonet J, Navarro R, Muñoz-Briones C, Sørensen KM, Mølgaard K, Oliva B, Sanz L, Blanco FJ, Alvarez-Vallina L. Intramolecular trimerization, a novel strategy for making multispecific antibodies with controlled orientation of the antigen binding domains. Sci Rep, 2016; 6: 28643 . PMID: 27345490 . DOI: 10.1038/srep28643.

2016