Original articles in indexed journals - Integrative Biomedical Informatics - Structural Bioinformatics

Salgado-Mendialdúa V, Aguirre-Plans J, Guney E, Reig-Viader R, Maldonado R, Bayés À, Oliva B, Ozaita A. Delta9-tetrahydrocannabinol modulates the proteasome system in the brain. Biochem Pharmacol, 2018;  pii: S0006-2952 (18) 30352-6. PMID: 30134192 . DOI: 10.1016/j.bcp.2018.08.026.

2018

Original articles in indexed journals - Computational Science

Skalic M, Martínez-Rosell G, Jiménez J, De Fabritiis G. PlayMolecule BindScope: Large scale CNN-based virtual screening on the web. Bioinformatics bty758, 2018. PMID: 30169549 . DOI: 10.1093/bioinformatics/bty758.

2018

Original articles in indexed journals - Computational RNA Biology

Singh B, Trincado JL, Tatlow PJ, Piccolo SR, Eyras E. Genome Sequencing and RNA-motif Analysis Reveal Novel Damaging Non-coding Mutations in Human Tumors. Mol Cancer Res, 2018; 16(7): 1112-1124. PMID: 29592900 . DOI: 10.1158/1541-7786.MCR-17-0601.

2018

Original articles in indexed journals - Integrative Biomedical Informatics

Speck-Planche A. Recent advances in fragment-based computational drug design: tackling simultaneous targets/biological effects. Future Med Chem, 2018; 10(17): 2021-2024. PMID: 30058835 . DOI: 10.4155/fmc-2018-0213.

2018

Original articles in indexed journals - GPCR Drug Discovery

Stepniewski TM, Torrens-Fontanals M, Rodríguez – Espigares I, Giorgino T, Primdahl KG, Vik A, Stenstrøm Y, Selent J, Hansen TV. Synthesis, molecular modelling studies and biological evaluation of new oxoeicosanoid receptor 1 agonists. Bioorgan Med Chem, 2018; 26, 12: 3580-3587. PMID: 29866479 . DOI: 10.1016/j.bmc.2018.05.036.

2018

Original articles in indexed journals - PharmacoInformatics

Radchenko T, Fontaine F, Morettoni L, Zamora I. WebMetabase: cleavage sites analysis tool for natural and unnatural substrates from diverse data source. Bioinformatics, 2018; bty667 . PMID: 30052776 . DOI: 10.1093/bioinformatics/bty667.

2018

Original articles in indexed journals - Computational Science

Skalic M, Varela-Rial A, Jiménez J, Martínez-Rosell G, De Fabritiis G. LigVoxel: Inpainting binding pockets using 3D-convolutional neural networks Bioinformatics, 2018; 35 (2): 243-250 15 . PMID: 29982392 . DOI: 10.1093/bioinformatics/bty667.

2018

Original articles in indexed journals - Computational RNA Biology

Jayasinghe RG, Cao S, Gao Q, Wyczalkowski MA, Sengupta S, Walter MJ and the Splicing Analysis Working Group (including Eyras E). Comprehensive portrait of canonical and non-canonical splicing in cancer. Cancer Research, 2018; 78 (13 Supplement): 2362. DOI: 10.1158/1538-7445.AM2018-2362.

2018

Original articles in indexed journals - Integrative Biomedical Informatics - Structural Bioinformatics

Aguirre-Plans J, Piñero J, Menche J, Sanz F, Furlong LI, Schmidt HHHW, Oliva B, Guney E. Proximal Pathway Enrichment Analysis for Targeting Comorbid Diseases via Network Endopharmacology. Pharmaceuticals, 2018; 11(3): E61.. PMID: 29932108 . DOI: 10.3390/ph11030061.

2018

Original articles in indexed journals - Integrative Biomedical Informatics - Structural Bioinformatics

Cuadrado A, Manda G, Hassan A, Alcaraz MJ, Barbas C, Daiber A, Ghezzi P, León R, López MG, Oliva B, Pajares M, Rojo AI, Robledinos-Antón N, Valverde AM, Guney E, Schmidt HHHW. Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach. Pharmacol Rev, 2018; 70(2): 348-383. PMID: 29507103 . DOI: 10.1124/pr.117.014753.

2018