Original articles in indexed journals - Integrative Biomedical Informatics

Dumontier M, Baker CJO, Baran J, Callahan A, Chepelev L, Cruz-Toledo J, Del Rio NR, Duck G, Furlong LI, Keath N, Klassen D, McCusker JP, Queralt-Rosinach N, Samwald M, Villanueva-Rosales N, Wilkinson MD, Hoehndorf R. The Semanticscience Integrated Ontology (SIO) for biomedical research and knowledge discovery. J Biom Sem, 2014; 5:14 DOI: 10.1186/2041-1480-5-14.

2014

Original articles in indexed journals - Computational RNA Biology

Raj B, Irimia M, Braunschweig U, Sterne-Weiler T, O'Hanlon D, Lin ZY, Chen GI, Easton LE, Ule J, Gingras AC, Eyras E, Blencowe BJ. A Global Regulatory Mechanism for Activating an Exon Network Required for Neurogenesis. Mol Cell, 2014. PMID: 25219497 . DOI: 10.1016/j.molcel.2014.08.011.

2014

Original articles in indexed journals - Computational RNA Biology

Alló M, Agirre E, Bessonov S, Bertucci P, Gómez Acuña L, Buggiano V, Bellora N, Singh B, Petrillo E, Blaustein M, Miñana B, Dujardin G, Pozzi B, Pelisch F, Bechara E, Agafonov DE, Srebrow A, Lührmann R, Valcárcel J, Eyras E, Kornblihtt AR. Argonaute-1 binds transcriptional enhancers and controls constitutive and alternative splicing in human cells. Proc Natl Acad Sci U S A, 2014; 111 (44): 15622-15629. PMID: 25313066 . DOI: 10.1073/pnas.1416858111.

2014

Original articles in indexed journals - Integrative Biomedical Informatics - PharmacoInformatics - GPCR Drug Discovery

Martí-Solano M, Sanz F, Pastor M, Selent J. A dynamic view of molecular switch behavior at serotonin receptors: implications for functional selectivity. PLoS One, 2014; 9(10): e109312 . PMID: 25313636 . DOI: 10.1371/journal.pone.0109312.

2014

Original articles in indexed journals - Computational Science

Stanley N, Esteban S*, de Fabritiis G*. Kinetic modulation of a disordered protein domain by phosphorylation. Nat Commun, 2014; 5: 5272. PMID: 25348080 . DOI: 10.1038/ncomms6272.

2014

PhD Thesis - Systems Pharmacology

Antolín A. The impact of polypharmacology on chemical biology. Universitat Pompeu Fabra. October 9th, 2014. Thesis Director: Mestres J.

2014

Original articles in indexed journals - GPCR Drug Discovery

Magnani F, Pappas C, Crook T, Magafa V, Cordopatis P, Ishiguro S, Ohta N, Selent J, Bosnyak S, Jones ES, Gerothanassis I, Tamura M, Widdop ER, Tzakos AG. Sculpting GPCR peptide-ligand subtype selectivity: tackling cancer via a novel drug target. Journal of Peptide Science, 2014; 20 S40-S41

2014

Original articles in indexed journals - Integrative Biomedical Informatics

Grosdidier S, Ferrer A, Faner R, Piñero J, Roca J, Cosío B, Agustí A, Gea J, Sanz F, Furlong LI. Network medicine analysis of COPD multimorbidities. Respir Res, 2014; 15(1): 111. PMID: 25248857 . DOI: 10.1186/s12931-014-0111-4.

2014

Original articles in indexed journals - Systems Pharmacology

Schmidt F, Amberg A, Mulliner D, Stolte M, Matter H, Hessler G, Dietrich A, Remez N, Vidal D, Mestres J, Czich A. Computational prediction of off-target related safety liabilities of molecules: Cardiotoxicity, hepatotoxicity and reproductive toxicity. Toxicol Let, 229 S164-S164; S DOI: 10.1016/j.toxlet.2014.06.564 SEP 10 2014.

2014

Original articles in indexed journals - Functional Genomics

Tur I, Roverato A, Castelo R. Mapping eQTL Networks with Mixed Graphical Markov Models. Genetics, 198 (4): 1377-1393
. PMID: 25271303 . DOI: 10.1534/genetics.114.169573 DEC 2014.

2014