Results 31 - 40 of about 99
Original articles in indexed journals - Systems Pharmacology - Computational Science
Ferruz N, Harvey M, Mestres J, de Fabritiis G. Insights from Fragment Hit Binding Assays by Molecular Simulations. J Chem Inf Model, 2015; 55 (10): 2200-2205 . PMID: 26376295 . DOI: 10.1021/acs.jcim.5b00453 OCT 2015.
2015
Original articles in indexed journals - Systems Pharmacology
Garcia-Serna R, Vidal D, Remez N, Mestres J. Large Scale Predictive Drug Safety: From Structural Alerts to Biological Mechanisms. Chem Res Toxicol, 2015; 28 (10): 1875-1887 . PMID: 26360911 . DOI: 10.1021/ acs.chemrestox. 5b00260.
2015
Original articles in indexed journals - Systems Pharmacology
Rubio-Perez C, Tamborero D, Schroeder MP, Antolin A, Deu-Pons J, Perez-Llamas C, Mestres J, Gonzalez-Perez A, Lopez-Bigas N. In Silico Prescription of Anticancer Drugs to Cohorts of 28 Tumor Types Reveals Targeting Opportunities. Cancer Cell, 2015; 27; 3: 319-321 . PMID: 25759023 . DOI: 10.1016/j.ccell.2015.02.007.
2015
Original articles in indexed journals - Systems Pharmacology
Baumann K, Ecker GF, Mestres J, Schneider G. Systems Approaches and Big Data in Molecular Informatics. Mol Inf, 34 (1): 2-2 DOI: 10.1002/minf.201580131 JAN 2015.
2015
Original articles in indexed journals - Systems Pharmacology
Antolin A, Mestres J. Distant Polypharmacology among MLP Chemical Probes. ACS Chem Biol, 2014;10 (2): 395-400
. PMID: 25365788 . DOI: 10.1021/cb500393m.
2014
Original articles in indexed journals - Systems Pharmacology
Schmidt F, Amberg A, Mulliner D, Stolte M, Matter H, Hessler G, Dietrich A, Remez N, Vidal D, Mestres J, Czich A. Computational prediction of off-target related safety liabilities of molecules: Cardiotoxicity, hepatotoxicity and reproductive toxicity. Toxicol Let, 229 S164-S164; S DOI: 10.1016/j.toxlet.2014.06.564 SEP 10 2014.
2014
Original articles in indexed journals - Integrative Biomedical Informatics - Systems Pharmacology
Horvath D, Lisurek M, Rupp B, Kühne R, Specker E, von Kries J, Rognan D, Andersson CD, Almqvist F, Elofsson M, Enqvist PA, Gustavsson AL, Remez N, Mestres J, Marcou G, Varnek A, Hibert M, Quintana J, Frank R. Design of a General-Purpose European Compound Screening Library for EU-OPENSCREEN. ChemMedChem, 2014; 9 (10):2309-2326. PMID: 25044981 . DOI: 10.1002/cmdc.201402126.
2014
Original articles in indexed journals - Systems Pharmacology
Antolín AA, Mestres J. Linking off-target kinase pharmacology to the differential cellular effects observed among PARP inhibitors. Oncotarget, 2014; 5 (10): 3023- 3028 . PMID: 24632590 . DOI: 10.18632/oncotarget.1814.
2014
Original articles in indexed journals - Systems Pharmacology
Spitzmüller A, Mestres J. Identification of host interactions for phenotypic antimalarial hits. J Cheminformatics, 2014; 6(Suppl 1):O12 . PMID: 24765110 .
2014
Original articles in indexed journals - Systems Pharmacology
Garcia-Reyero N, Escalon BL, Prats E, K Stanley J, Thienpont B, Melby NL, Barón E, Eljarrat E, Barceló D, Mestres J, Babin PJ, Perkins EJ, Raldúa D. Effects of BDE-209 contaminated sediments on zebrafish development and potential implications to human health. Environ Int. 2013 Dec 5;63C:216-223. PMID: 24317228 . DOI: 10.1016/j.envint.2013.11.012.
2013