Original articles in indexed journals - Systems Pharmacology

Olivés J, Mestres J. Closing the Gap between Therapeutic Use and Mode of Action in Remedial Herbs. Front Pharmacol, 2019; 10: 1132. PMID: 31632273 . DOI: 10.3389/fphar.2019.01132.

2019

Original articles in indexed journals - Systems Pharmacology

Dyballa S, Miñana R, Rubio-Brotons M, Cornet C, Pederzani T, Escaramis G, Garcia-Serna R, Mestres J, Terriente J. Comparison of zebrafish larvae and hiPSC cardiomyocytes for predicting drug induced cardiotoxicity in humans. Toxicol Sci, 2019. PMID: 31359052 . DOI: 10.1093/toxsci/kfz165.

2019

Original articles in indexed journals - Systems Pharmacology

Bofill A, Jalencas X, Oprea TI, Mestres J. The human endogenous metabolome as a pharmacology baseline for drug discovery. Drug Discovery Today, 2019; pii: S1359-6446 (19) 30104- 7. PMID: 31226432 . DOI: 10.1016/ j.drudis.2019.06.007.

2019

Original articles in indexed journals - Systems Pharmacology

Vogt I, Mestres J. Information Loss in Network Pharmacology. Mol Inf, 2019; 38: 1900032. PMID: 30957433 . DOI: 10.1002/ minf.201900032.

2019

Original articles in indexed journals - Integrative Biomedical Informatics - Systems Pharmacology

Brennecke at al (including Quintana J, Mestres J). EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology. SLAS Discov, 2019; 11: 247255521881627. PMID: 30616481 . DOI: 10.1177/ 2472555218816276.

2019

Original articles in indexed journals - Systems Pharmacology

Antolín AA, Mestres J. Dual Inhibitors of PARPs and ROCKs. ACS Omega, 2018; 3 (10): 12707-12712. PMID: 30411017 . DOI: 10.1021/acsomega.8b02337.

2018

Original articles in indexed journals - Integrative Biomedical Informatics - Systems Pharmacology - PharmacoInformatics

Sanz F, Pognan F, Steger-Hartmann T, Díaz C, Cases M, Pastor M, Marc P, Wichard J, Briggs K, Watson D, Kleinöder T, Yang C, Amberg A, Beaumont M, Brookes A, Brunak S, Cronin MTD, Ecker GF, Escher S, Greene N, Guzmán A, Hersey A, Jacques P, Lammens L, Mestres J, Muster W, Northeved H, Pinches M, Saiz J, Sajot N, Valencia A, van der Lei J, Vermeulen NPE, Vock E, Wolber G, Zamora I. Legacy data sharing to improve drug safety assessment: the eTOX project. Nature Reviews Drug Discovery, 2017; 16(12): 811-812. PMID: 29026211 . DOI: 10.1038/nrd.2017.177.

2017

Original articles in indexed journals - Systems Pharmacology

Sultana J, Calabró M, Garcia-Serna R, Ferrajolo C, Crisafulli C, Mestres J, Trifirò' G. Biological substantiation of antipsychotic-associated pneumonia: Systematic literature review and computational analyses. PLoS ONE, 2017; 12(10): e0187034. PMID: 29077727 .

2017

Original articles in indexed journals - Systems Pharmacology

Concu R, Kleandrova VV, Speck-Planche A, Cordeiro MNDS. Probing the Toxicity of Nanoparticles: a Unified In Silico Machine Learning Model based on Perturbation Theory. Nanotoxicology 2017; 11(7): 891-906 . PMID: 10.1080/17435390.2017.1379567 . DOI: 28937298.

2017

Original articles in indexed journals - Systems Pharmacology

Kumar R, Yadav N, Lavilla R, Blasi D, Quintana J, Brea JM, Loza MI, Mestres J, Bhandari M, Arora R, Kakkar R, Prasad AK. Synthesis, pharmacological evaluation and molecular docking of pyranopyrazole-linked 1,4-dihydropyridines as potent positive inotropes. Mol Divers, 2017; 21; 3:  533-546. PMID: 28444482 . DOI: 10.1007/s11030-017-9738-7.

2017