Original articles in indexed journals - Systems Pharmacology

Baumann K, Ecker GF, Mestres J, Schneider G. Sustained Success of Molecular Informatics. Mol Inform, 2013;32(1):3-3 SI DOI: 10.1002/minf.201380132.

2013

Original articles in indexed journals - Systems Pharmacology

Oprea TI, Mestres J. Drug Repurposing: Far Beyond New Targets for Old Drugs. AAPS Journal, 2012; 14(4): 759-763 . PMID: 22826034 . DOI: 10.1208/s12248-012-9390-1.

2012

Original articles in indexed journals - Systems Pharmacology

Montolio M, Gregori-Puigjane E, Pineda D, Mestres J, Navarro P. Identification of small molecule inhibitors of Amyloid ?-induced neuronal apoptosis acting through the imidazoline I2 receptor. J Med Chem, 2012; 55 (22): 9838-9846. PMID: 23098038 . DOI: 10.1021/jm301055g.

2012

Original articles in indexed journals - Systems Pharmacology

Antolín AA, Jalencas X, Yélamos J, Mestres J. Identification of Pim Kinases as Novel Targets for PJ34 with Confounding Effects in PARP Biology. ACS Chem Biol, 2012; 7 (12); 1962–1967. PMID: 23025350 . DOI: 10.1021/cb300317y.

2012

Original articles in indexed journals - Systems Pharmacology

Baumann K, Ecker, GF, Mestres J, Schneider G. Editorial: Molecular Informatics Gaining Impact. Mol Inf, 2012; 31 (9):615-615. DOI: 10.1002/minf.201280931.

2012

Other - Integrative Biomedical Informatics - Systems Pharmacology

Coloma PM, Schuemie MJ, Trifiro G, Furlong L, Van Mulligen E, Bauer-Mehren A, Avillach P, Kors J, Sanz F, Mestres J, Oliveira JL, Boyer S, Helgee EA, Molokhia M, Matthews J, Prieto-Merino D, Gini R, Herings RMC, Mazzaglia G, Picelli G, Scotti L, Pedetsen L, Van der Lei J, Sturkenboom MCJM. Triage and Evaluation of Potential Safety Signals Identified from Electronic Healthcare Record Databases. Drug Safety, 2012; 35 (10): 905-905

2012

Original articles in indexed journals - Systems Pharmacology

Areias F, Costa M, Castro M et al. New chromene scaffolds for adenosine A(2A) receptors: Synthesis, pharmacology and structure-activity relationships. Eur J Med Chem, 2012; 54: 303-10. PMID: 22677030 . DOI: 10.1016/j.ejmech.2012.05.009.

2012

Original articles in indexed journals - Systems Pharmacology

Carrascosa MC, Massaguer OL, Mestres J. PharmaTrek: A Semantic Web Explorer for Open Innovation in Multitarget Drug Discovery. Mol Inf, 2012; 31 (8):537-541. PMID: 23548981 . DOI: 10.1002/minf.201200070.

2012

Original articles in indexed journals - Systems Pharmacology

Gallastegui E, Marshall B, Vidal D, Sánchez G, Sánchez S, Collado JA, Luque N, Terme J-M, Gatell JM, Muñoz E, Mestres J, Verdin E, Jordan A. Combination of Biological Screening in a Cellular Model of Viral Latency with Virtual Screening Identifies Novel Compounds that Reactivate HIV-1. Journal of Virology, 2012; 86, 3795-3808. PMID: 22258251 . DOI: 10.1128/JVI.05972-11.

2012

Original articles in indexed journals - Integrative Biomedical Informatics - Systems Pharmacology

Bauer-Mehren A, van Mulligen EM, Avillach P, Carrascosa MC, Garcia-Serna R, Piñero J, Singh B, Lopes P, Oliveira JL, Diallo G, Ahlberg Helgee E, Boyer S, Mestres J, Sanz F, Kors JA, Furlong LI. Automatic Filtering and Substantiation of Drug Safety Signals. PLoS Comput Biol, 2012; 8(4); e1002457. PMID: 22496632 . DOI: 10.1371/journal.pcbi.1002457.

2012