PhD Thesis - Systems Pharmacology

Olivés J. Endogenous Metabolites in Drug Discovery: from Plants to Human. Universitat Pompeu Fabra. January, 30th 2017. Thesis Director: Mestres J.

2017

Reviews in indexed journals - Systems Pharmacology - Computational Science

Ferruz N, Harvey MJ, Mestres J, De Fabritiis G. Insights from Fragment Hit Binding Assays by Molecular Simulations (vol 55, pg 2200, 2015). J Chem Inf Model, 2016; 56 (10):2123-2123 . PMID: 26376295 . DOI: 10.1021/acs.jcim.6b00557 OCT 2016.

2016

Original articles in indexed journals - Systems Pharmacology

Antolin AA, Workman P, Mestres J, Al-Lazikani B. Polypharmacology in Precision Oncology: Current Applications and Future Prospects. Curr Pharm Des, 2016; 22 (46): 6935-6945 . PMID: 27669965 . DOI: 10.1174/1381611811666160913115818 2016.

2016

Original articles in indexed journals - Systems Pharmacology

Van Voorhis WC, Adams JH, Adelfio R, Ahyong V, Akabas MH, Alano P, Alday A, Alemán Resto Y, Alsibaee A, Alzualde A, Andrews KT, Avery SV et al (including Mestres J). Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond. PLoS Pathog, 2016; 12(7): e1005763. . PMID: 27467575 . DOI: 10.1371/journal.ppat.1005763. eCollection 2016.

2016

Original articles in indexed journals - Systems Pharmacology

Remez N, Garcia-Serna R, Vidal D, Mestres J. The In Vitro Pharmacological Profile of Drugs as a Proxy Indicator of Potential In Vivo Organ Toxicities. Chem Res Toxicol, 2016; 29: 637−648 . PMID: 26952164 . DOI: 10.1021/acs.chemrestox.5b00470.

2016

Reviews in indexed journals - Systems Pharmacology

Bousquet J, Anto JM, Akdis M, Auffray C, Keil T, Momas I, Postma D, Valenta R, Wickman M, Cambon-Thomsen A, Haahtela T, Lambrecht BN, Lodrup-Carlsen K, Koppelman GH, Sunyer J, Zuberbier T, Annesi-Maesano I, Arno A, Bindslev-Jensen C, De Carlo G, Forastiere F, Heinrich J, Kowalski ML, Maier D, Melén E, Palkonen S, Smit HA, Standl M, Wright J, Arsanoj A, Benet M, Balardini N, Garcia-Aymerich J, Gehring U, Guerra S, Hohman C, Kull I, Lupinek C, Pinart M, Skrindo I, Westman M, Smagghe D, Akdis C, Albang R, Anastasova V, Anderson N, Bachert C, Ballereau S, Ballester F, Basagana X, Bedbrook A, Bergstrom A, von Berg A, Brunekreef B, Burte E, Carlsen KH, Chatzi L, Coquet JM, Curin M, Demoly P, Eller E, Fantini MP, Gerhard B, Hammad H, von Hertzen L, Hovland V, Jacquemin B, Just J, Keller T, Kerkhof M, Kiss R, Kogevinas M, Koletzko S, Lau S, Lehmann I, Lemonnier N, McEachan R, Mäkelä M, Mestres J, Minina E, Mowinckel P, Nadif R, Nawijn M, Oddie S, Pellet J, Pin I, Porta D, Rancière F, Rial-Sebbag A, Saes Y, Schuijs MJ, Siroux V, Tischer CG, Torrent M, Varraso R, De Vocht J, Wenger K, Wieser S, Xu C. Paving the way of systems biology and precision medicine in allergic diseases: the MeDALL success story Mechanisms of the Development of ALLergy; EUFP7-CP-IP; Project No: 261357; 2010-2015. Allergy, 2016; 71 (11): 1513-1525 . PMID: 26970340 . DOI: 10.1111/all.12880.

2016

PhD Thesis - Systems Pharmacology

Remez N. Drug design at biological systems level. University Pompeu Fabra. Thesis Director: Mestres J. February 8, 2016.

2016

Original articles in indexed journals - Systems Pharmacology

Baumann K, Ecker GF, Mestres J, Schneider G. Molecular Informatics: From Models to Systems and Beyond. Mol Inf, 2016; 35 (1): 2-2 DOI: 10.1002/minf.201680133.

2016

Original articles in indexed journals - Systems Pharmacology

Rubio-Perez C, Tamborero D, Schroeder MP, Antolin AA, Deu-Pons J, Perez-Llamas C, Mestres J, Gonzalez-Perez A, Lopez-Bigas N. In silico prescription of anticancer drugs to cohorts of 28 tumor types reveals novel targeting opportunities. Cancer Res, 2015; 75 (22): 1 DOI: 10.1158/1538-7445.TRANSCAGEN-A1-45.

2015

Original articles in indexed journals - Systems Pharmacology - Computational Science

Ferruz N, Harvey M, Mestres J, de Fabritiis G. Insights from Fragment Hit Binding Assays by Molecular Simulations. J Chem Inf Model, 2015; 55 (10): 2200-2205 . PMID: 26376295 . DOI: 10.1021/acs.jcim.5b00453 OCT 2015.

2015