Original articles in indexed journals - Computational Genomics - group

Gonzalez-Perez A, Deu-Pons J, Lopez-Bigas N. Improving the prediction of the functional impact of cancer mutations by baseline tolerance transformation. Genome Med, 2012; 4(11):89. PMID: 23181723 .

2012

Original articles in indexed journals - Computational Genomics - group - Functional Genomics

Roverato A, Castelo R. Learning undirected graphical models from multiple datasets with the generalized non-rejection rate. International Journal of Approximate Reasoning, 2012; 53; 9: 1326–1335 DOI: 10.1016/j.ijar.2012.05.007.

2012

Original articles in indexed journals - Computational Genomics - group

Gonzalez-Perez A, Lopez-Bigas N. Functional impact bias reveals cancer drivers. Nucleic Acids Res, 2012; 40; 21: e169. PMID: 22904074 . DOI: 10.1093/nar/gks743.

2012

Original articles in indexed journals - Computational Genomics - group

Bayarmagnai B, Nicolay BN, Islam AB, Lopez-Bigas N, Frolov MV. Drosophila GAGA factor is required for full activation of the dE2F1-Yki/Sd transcriptional program. Cell Cycle, 2012;11(22) : 4191-4202. PMID: 23070566 . DOI: 10.4161/cc.22486.

2012

Original articles in indexed journals - Computational Genomics - group

Beshiri ML, Holmes KB, Richter WF, Hess S, Islam AB, Yan Q, Plante L, Litovchick L, Gévry N, Lopez-Bigas N, Kaelin WG Jr, Benevolenskaya EV. Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation. P Natl Acad Sci USA, 2012;  109 (45): 18499-18504. PMID: 23093672 . DOI: 10.1073/pnas.1216724109.

2012

Original articles in indexed journals - Computational Genomics - group

Pippa R, Espinosa L, Gundem G, Garcia-Escudero R, Dominguez A, Orlando S, Gallastegui E, Saiz C, Besson A, Pujol MJ, Lopez-Bigas N, Paramio JM, Bigas A, Bachs O. p27(Kip1) represses transcription by direct interaction with p130/E2F4 at the promoters of target genes. Oncogene, 2012; 31 (38):4207-4220. PMID: 22179826 . DOI: 10.1038/onc.2011.582.

2012

Original articles in indexed journals - Computational RNA Biology - Computational Genomics - group

Nadal-Ribelles M, Conde N, Flores O, Gonzalez-Vallinas J, Eyras E, Orozco M, de Nadal E, Posas F. Hog1 bypasses stress-mediated down-regulation of transcription by RNA polymerase II redistribution and chromatin remodeling. Genome Biol, 2012; 13(11): R106. PMID: 23158682 . DOI: 10.1186/gb-2012-13-11-r106 2012.

2012

Original articles in indexed journals - Computational Genomics - group - Functional Genomics

Mahdi T, Hanzelmann S, Salehi A et al. Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes. Cell metabolism, 2012; 16; 5: 625-33. PMID: 23140642 . DOI: 10.1016/j.cmet.2012.10.009.

2012

PhD Thesis - Computational Genomics - group - Functional Genomics

Hänzelmann S. Pathway-centric approaches to the analysis of high-throughput genomics data. University Pompeu Fabra. Director: Castelo R. October, 11 2012.

2012

Original articles in indexed journals - Computational Genomics - group

Ng S, Collisson EA, Sokolov A, Goldstein T, Gonzalez-Perez A, Lopez-Bigas N, Benz C, Haussler D, Stuart JM. PARADIGM-SHIFT predicts the function of mutations in multiple cancers using pathway impact analysis. Bioinformatics, 2012; 15;28(18): i640-i646. PMID: 22962493 . DOI: 10.1093/bioinformatics/bts402.

2012