Results 71 - 80 of about 213
Original articles in indexed journals - Integrative Biomedical Informatics
Piñero J, Furlong LI, Sanz F. In silico models in drug development: where we are. Curr Opin Pharmacol, 2018; 42: 111-121.. PMID: 30205360 . DOI: 10.1016/j.coph.2018.08.007.
2018
Original articles in indexed journals - Integrative Biomedical Informatics - Structural Bioinformatics
Piñero J, Gonzalez-Perez A, Guney E, Aguirre-Plans J, Sanz F, Oliva B, Furlong LI. Network, Transcriptomic and Genomic Features Differentiate Genes Relevant for Drug Response. Front Genet, 2018; 9: 412. PMID: 30319692 . DOI: 10.3389/fgene.2018.00412.
2018
Original articles in indexed journals - Integrative Biomedical Informatics
Gomez-Rubio P, Piñero J, Molina-Montes E, Gutiérrez-Sacristán A, Marquez M, Rava M, Michalski CW, Farré A, Molero X, Löhr M, Perea J, Greenhalf W, O'Rorke M, Tardón A, Gress T, Barberà VM, Crnogorac-Jurcevic T, Muñoz-Bellvís L, Domínguez-Muñoz E, Balsells J, Costello E, Yu J, Iglesias M, Ilzarbe L, Kleeff J, Kong B, Mora J, Murray L, O'Driscoll D, Poves I, Lawlor RT, Ye W, Hidalgo M, Scarpa A, Sharp L, Carrato A, Real FX, Furlong LI, Malats N. PanGenEU Study Investigators.. Pancreatic cancer and autoimmune diseases: An association sustained by computational and epidemiological case-control approaches. Int J Cancer, 2018; 144(7): 1540-1549. PMID: 30229903 . DOI: 10.1002/ijc.31866.
2018
Original articles in indexed journals - Integrative Biomedical Informatics - Structural Bioinformatics
Salgado-Mendialdúa V, Aguirre-Plans J, Guney E, Reig-Viader R, Maldonado R, Bayés À, Oliva B, Ozaita A. Delta9-tetrahydrocannabinol modulates the proteasome system in the brain. Biochem Pharmacol, 2018; pii: S0006-2952 (18) 30352-6. PMID: 30134192 . DOI: 10.1016/j.bcp.2018.08.026.
2018
Original articles in indexed journals - Integrative Biomedical Informatics
Speck-Planche A. Recent advances in fragment-based computational drug design: tackling simultaneous targets/biological effects. Future Med Chem, 2018; 10(17): 2021-2024. PMID: 30058835 . DOI: 10.4155/fmc-2018-0213.
2018
Original articles in indexed journals - Integrative Biomedical Informatics - Structural Bioinformatics
Aguirre-Plans J, Piñero J, Menche J, Sanz F, Furlong LI, Schmidt HHHW, Oliva B, Guney E. Proximal Pathway Enrichment Analysis for Targeting Comorbid Diseases via Network Endopharmacology. Pharmaceuticals, 2018; 11(3): E61.. PMID: 29932108 . DOI: 10.3390/ph11030061.
2018
Original articles in indexed journals - Integrative Biomedical Informatics - Structural Bioinformatics
Cuadrado A, Manda G, Hassan A, Alcaraz MJ, Barbas C, Daiber A, Ghezzi P, León R, López MG, Oliva B, Pajares M, Rojo AI, Robledinos-Antón N, Valverde AM, Guney E, Schmidt HHHW. Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach. Pharmacol Rev, 2018; 70(2): 348-383. PMID: 29507103 . DOI: 10.1124/pr.117.014753.
2018
Original articles in indexed journals - Integrative Biomedical Informatics
Gutiérrez-Sacristán A, Bravo A, Giannoula A, Mayer MA, Sanz F, Furlong LI. comoRbidity: An R package for the systematic analysis of disease comorbidities. Bioinformatics, 2018; 34 (18): 3228-30. PMID: 29897411 . DOI: 10.1093/ bioinformatics/ bty315.
2018
Original articles in indexed journals - Integrative Biomedical Informatics - PharmacoInformatics
López-Massaguer O, Pinto-Gil K, Sanz F, Amberg A, Anger LT, Stolte M, Ravagli C, Marc P, Pastor M. Generating modelling data from repeat-dose toxicity reports. Toxicol Sci, 2018; 162(1): 287-300. PMID: 29155963 . DOI: 10.1093/toxsci/kfx254.
2018
Original articles in indexed journals - Integrative Biomedical Informatics
Giannoula A, Gutierrez Sacristán A, Bravo A, Sanz F, Furlong LI. Identifying temporal patterns in patient disease trajectories using dynamic time warping: A population-based study. Sci Rep, 2018; 8(1): 4216. PMID: 29523868 . DOI: 10.1038/s41598-018-22578-1.
2018