Results 201 - 210 of about 1076
Original articles in indexed journals - Integrative Biomedical Informatics
Speck-Planche A. Combining Ensemble Learning with a Fragment-Based Topological Approach To Generate New Molecular Diversity in Drug Discovery: In Silico Design of Hsp90 Inhibitors. ACS Omega, 2018; 3(11): 14704- 14716. PMID: 30555986 . DOI: 10.1021/acsomega.8b02419.
2018
Original articles in indexed journals - Evolutionary Genomics
Ruiz-Orera J, Alba MM. Translation of Small Open Reading Frames: Roles in Regulation and Evolutionary Innovation. Trends Genet, 2018; 35(3): 186-198. PMID: 30606460 . DOI: 10.1016/j.tig.2018.12.003.
2018
Original articles in indexed journals - Computational Science
Jiménez Luna J, Sabbadin D, Cuzzolin A, Martínez-Rosell G, Gora J, Manchester J, Duca JS, De Fabritiis G. PathwayMap: Molecular pathway association with self-normalizing neural networks. J Chem Inf Model, 2018; 59(3): 1172-1181. PMID: 30586501 . DOI: 10.1021/acs.jcim.8b00711.
2018
Original articles in indexed journals - Integrative Biomedical Informatics
Souza T, Trairatphisan P, Piñero J, Furlong LI, Saez-Rodriguez J, Kleinjans J, Jennen D. Embracing the Dark Side: Computational Approaches to Unveil the Functionality of Genes Lacking Biological Annotation in Drug-Induced Liver Injury. Front Genet, 2018; 9:527 . PMID: 30515189 . DOI: 10.3389/ fgene. 2018.00527.
2018
Original articles in indexed journals - Integrative Biomedical Informatics
Speck-Planche A, Scotti MT. BET bromodomain inhibitors: fragment-based in silico design using multi-target QSAR models. Mol Divers, 2018; 23(3): 555-572. PMID: 30421269 . DOI: 10.1007/s11030-018-9890-8.
2018
Original articles in indexed journals - Systems Pharmacology
Antolín AA, Mestres J. Dual Inhibitors of PARPs and ROCKs. ACS Omega, 2018; 3 (10): 12707-12712. PMID: 30411017 . DOI: 10.1021/acsomega.8b02337.
2018
Original articles in indexed journals - Integrative Biomedical Informatics - PharmacoInformatics
Pastor M, Quintana J, Sanz F. Development of an Infrastructure for the Prediction of Biological Endpoints in Industrial Environments. Lessons Learned at the eTOX Project. Front Pharmacol, 2018; 9: 1147. PMID: 30364191 . DOI: 10.3389/fphar.2018.01147.
2018
Original articles in indexed journals - Integrative Biomedical Informatics
Piñero J, Furlong LI, Sanz F. In silico models in drug development: where we are. Curr Opin Pharmacol, 2018; 42: 111-121.. PMID: 30205360 . DOI: 10.1016/j.coph.2018.08.007.
2018
Original articles in indexed journals - Integrative Biomedical Informatics - Structural Bioinformatics
Piñero J, Gonzalez-Perez A, Guney E, Aguirre-Plans J, Sanz F, Oliva B, Furlong LI. Network, Transcriptomic and Genomic Features Differentiate Genes Relevant for Drug Response. Front Genet, 2018; 9: 412. PMID: 30319692 . DOI: 10.3389/fgene.2018.00412.
2018
Original articles in indexed journals - Integrative Biomedical Informatics
Gomez-Rubio P, Piñero J, Molina-Montes E, Gutiérrez-Sacristán A, Marquez M, Rava M, Michalski CW, Farré A, Molero X, Löhr M, Perea J, Greenhalf W, O'Rorke M, Tardón A, Gress T, Barberà VM, Crnogorac-Jurcevic T, Muñoz-Bellvís L, Domínguez-Muñoz E, Balsells J, Costello E, Yu J, Iglesias M, Ilzarbe L, Kleeff J, Kong B, Mora J, Murray L, O'Driscoll D, Poves I, Lawlor RT, Ye W, Hidalgo M, Scarpa A, Sharp L, Carrato A, Real FX, Furlong LI, Malats N. PanGenEU Study Investigators.. Pancreatic cancer and autoimmune diseases: An association sustained by computational and epidemiological case-control approaches. Int J Cancer, 2018; 144(7): 1540-1549. PMID: 30229903 . DOI: 10.1002/ijc.31866.
2018