Tools
Modlink
Improving the fold recognition by using protein-protein interactions. Developed by the Structural Bioinformatics group.
PEAKS
The positional footprinting web server. PEAKS can be used to identify significant motif positional biases in DNA sequences. Developed by the Evolutionary Genomics group.
Pentacle
Pentacle is an advanced software tool for computing, handling and interpreting GRid INdependent Descriptors (GRIND). It was born as a replacement of the pioneering ALMOND software. All our experience in the practical application of GRIND was applied to obtain a powerful, flexible and friendly tool. Developed by the PharmacoInformatics group.
PROMO
PROMO is a virtual laboratory for the identification of putative transcription factor binding sites (TFBS) in DNA sequences from a species or groups of species of interest. TFBS defined in the TRANSFAC database are used to construct specific binding site weight matrices for TFBS prediction. The user can inspect the result of the search through a graphical interface and downloadable text files.
qpgraph
Estimation of genetic and molecular regulatory networks from high-throughput genomics data. Developed by the Functional Genomics group.
Shop
Advanced Scaffold Hopping and beyond.The final result of many computational tools and methods used in drug discovery is a mathematical model or a 3D graphic. However, drug design aims to obtain real compounds, synthetically affordable. SHOP was developed around this central concept, as a tool able to provide solutions to diverse practical problems in terms of a list of synthetically accessible derivatives. Developed by the PharmacoInformatics group.
VIDA
VIDA is an online database for the classification of virus proteins into families. It contains alignments of conserved domains, and consistent functional and taxonomic annotations.
iPHACE
Developed by the Systems Pharmacology group, iPHACE is an integrative web-based tool to navigate in the pharmacological space defined by small molecule drugs contained in the IUPHAR-DB and PDSP databases. Extending beyond traditional querying and filtering tools, iPHACE offers a means to extract knowledge from the target profile of drugs as well as from the drug profile of protein targets.
