The new study published by the Albà group at GRIB investigates the properties of proteins that have evolved in recent times. The research finds that there is an excess of new duplicated and de novo proteins at the level of the species, which means that the majority of the newly arisen proteins are likely to function during a relatively short evolutionary period, and become invisible after that. Because of their non-coding origin, de novo evolved proteins tend to be small and positively charged. However, if retained for Millions of years, they start accumulating mutations that increase the percentage of acidic amino acids, and become larger. The work brings new light into the early evolution of proteins.
You can read more in this following link: https://academic.oup.com/mbe/advance-article/doi/10.1093/molbev/msad098/7151198