26/3/2013

eTOX in the spotlight in special issue of Molecular Informatics

IMI’s drug toxicity project eTOX features in a special issue of the journal Molecular Informatics dedicated to advances in computational technology, a field where eTOX is making significant progress with its computer-based tools and models to predict drug toxicity. The challenges in the field are set out in a guest editorial by eTOX team member Thomas Steger-Hartmann of Bayer. The issue itself includes two contributions from eTOX. One article of the GRIB members Montserrat Cases, Manuel Pastor and Ferran Sanz presents the eTOX public library, which is described as ‘a useful resource for affording the in silico toxicity prediction of novel drug candidates’. A second article signed by researchers of the partner AstraZeneca, discusses the challenge of screening potential drugs for unintended side effects.

Article reference: Cases M, Pastor M, Sanz F. The eTOX Library of Public Resources for in Silico Toxicity Prediction. Mol Inf, 2013. 32: 24–35. doi: 10.1002/minf.201200099

eTOX project is funded by the Innovative Medicines Initiative Joint Undertaking (IMI-JU).