Thesis defence of Karolina Kopánska: “Uncertainty analysis of individual predictions and integrated safety assessments in toxicology”
Last Thursday, 29th of February 2024, at 12:00, Karolina Kopánska, member of the PharmacoInformatics PhI group, has read her thesis and qualified with an Excellent CUM LAUDE: "Uncertainty analysis of individual predictions and integrated safety assessments in toxicology". It took place in room 61.127 of the UPF.
Animal experimentation in toxicology for the 21st century: needed or outdated?
Karolina Kopańska is a postgraduate student pursuing her doctorate in the field of computational toxicology in the PharmacoInformatics Group (GRIB/UPF) led by Manuel Pastor. She recently attended a Summer School on non-animal approaches in science, and here she shares her views after what she learned and what her experience has taught her.
She's interested in topics related with toxicological risk assessment and decision-making under uncertainty, and hopes to make further contributions to strengthen animal-free research in the future.
FBBVA - Development of novel transcriptome-informed methods to predict the response to immunotherapy in cancer
The goal of this project is to use DNA and RNA sequencing data collected from hundreds of patients with advanced bladder cancer, including a cohort at Hospital del Mar in Barcelona, to develop predictive models of the response to immunotherapy. We expect that, by including different types of neoantigens and new molecular biomarkers in the models, we will be able to achieve higher accuracy in the predictive models. The project is undertaken by a highly multidisciplinary team led by Mar Albà. The funding is for the period 2022-2024.
- La Chica Lhoëst MT, Martinez A, Claudi L, Garcia E, Benitez-Amaro A, Polishchuk A, Piñero J, Vilades D, Guerra JM, Sanz F, Rotllan N, Escolà-Gil JC and Llorente-Cortés V. Mechanisms modulating foam cell formation in the arterial intima: exploring new therapeutic opportunities in atherosclerosis. Front Cardiovasc Med, 2024; 11:1381520 DOI: 10.3389/fcvm.2024.1381520.
- Mortier P, Vilagut G, García-Mieres H, Alayo I, Ferrer M, Amigo F, Aragonès E, Aragón-Peña A, Asúnsolo Del Barco Á, Campos M, Espuga M, González-Pinto A, Haro JM, López Fresneña N, Martínez de Salázar AD, Molina JD, Ortí-Lucas RM, Parellada M, Pelayo-Terán JM, Pérez-Gómez B, Pérez-Zapata A, Pijoan JI, Plana N, Polentinos-Castro E, Portillo-Van Diest A, Puig T, Rius C, Sanz F, Serra C, Urreta-Barallobre I, Kessler RC, Bruffaerts R, Vieta E, Pérez-Solá V, Alonso J; MINDCOVID Working group. Health service and psychotropic medication use for mental health conditions among healthcare workers active during the Spain Covid-19 Pandemic - A prospective cohort study using web-based surveys. Psychiatry Res, 2024; 334:115800. PMID: 38387166 . DOI: 10.1016/j.psychres.2024.115800.
- Mortier et al (including Pastor M, Leis A, Mayer MA, Ramirez-Anguita JM and Sanz F). Developing a clinical decision supportsystem software prototype that assists in themanagement of patients with self-harm in theemergency department: protocol of the PERMANENS project. BMC Psychiatry (2024) 24:220 DOI: 10.1186/s12888-024-05659-6.
- Niarakis A et al (including Furlong LI, Piñero J). COVID-19 Disease Map Community. Drug-target identification in COVID-19 disease mechanisms using computational systems biology approaches. Front Immunol, 2024; 14: 1282859. doi: . PMID: 38414974; PMCID: PMC10897000.. PMID: 38414974 . DOI: 10.3389/fimmu.2023.1282859.
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